I-HCV(Ngokukhawuleza)

Uninzi lwezigulana azinazimpawu zicacileyo kwinqanaba elibukhali lokusuleleka, ehamba kunye namanqanaba aphezulu e-viremia kunye nokuphakama kwe-ALT.I-HCV RNA yavela egazini ngaphambi kwexesha kune-anti HCV emva kosulelo oluqatha lwe-HCV.I-HCV RNA inokufunyanwa kwiiveki ezi-2 emva kokuvezwa kwangoko, i-antigen engundoqo ye-HCV inokubonwa kwiintsuku ezi-1 ukuya kwezi-2 emva kokuvela kwe-HCV RNA, kwaye i-anti-HCV ayinakubonwa de kube ziiveki ezisi-8 ukuya kwezi-12, oko kukuthi, emva kosulelo lwe-HCV, kukho malunga ne-HCV RNA. Iiveki ze-8-12, kuphela i-HCV RNA inokufunyanwa, ngelixa i-anti-HCV ingalunganga, oko kukuthi, "ixesha lefestile" yokubhaqa i-anti HCV, kunye nobude bexesha "lefestile" lihambelana ne-reagent yokufumanisa (jonga i-Table 1 ).I-Anti HCV ayilo-antibody ekhuselayo, kodwa luphawu losulelo lwe-HCV.I-15% ~ 40% yezigulane ezinosulelo olubukhali lwe-HCV zinokususa usulelo kwiinyanga ezi-6.Kwinkqubo yokucoca usulelo, inqanaba le-HCV RNA linokuba liphantsi kakhulu ukuba lingabonwa, kwaye kuphela i-anti HCV efanelekileyo;Nangona kunjalo, i-65% ~ 80% yezigulane azizange zisuswe kwiinyanga ezi-6, ezibizwa ngokuba yi-HCV engapheliyo.Emva kokuba i-hepatitis C engapheliyo isenzeka, i-HCV RNA titer iqala ukuzinza, kwaye ukuchacha ngokuzenzekelayo kunqabile.Ngaphandle kokuba unyango lwe-antiviral olusebenzayo lwenziwa, ukucocwa okuzenzekelayo kwe-HCV RNA kunqabile ukuba kwenzeke.Kwinkqubo yonyango, uninzi lwezigulana ezine-hepatitis C engapheliyo ziphila ne-anti HCV (izigulana ezicinezelekileyo, ezifana nezigulana ezine-HIV, abamkeli bokufakelwa kwamalungu aqinileyo, abaguli abane-hypogammaglobulinemia okanye abaguli be-hemodialysis banokuba negative kwi-anti HCV), kunye ne-HCV RNA inokuba nethemba. okanye kakubi (inqanaba le-HCV RNA liphantsi emva konyango lwe-antiviral).