Imvelaphi:
Umhla woku-1 kuDisemba ngo-2022 luSuku lwe-AIDS lweHlabathi lwama-35.
NgoJulayi 2022, idatha yamva nje evela kwi-UNAIDS,Ingxelo yeNkqubela ye-AIDS ye-2022 yeGlobal: Amalungu abalulekileyoyabonisa ukuba inkqubela ekuphenduleni ubhubhane we-AIDS imile kule minyaka mibini idlulileyo, abantu abangama-650,000 emhlabeni wonke basabulawa zizifo ezinxulumene ne-AIDS (umyinge wokufa omnye ngomzuzu), malunga ne-1.5 yesigidi sosulelo olutsha lwe-HIV (i-1 yezigidi zeemeko ezingaphezu kwe-1. ekujoliswe kuko kwihlabathi jikelele), kunye nemeko yothintelo nolawulo lwe-AIDS kwihlabathi jikelele ihleli imbi.
Yintoni i-HIV?
Human immunodeficiency virus (HIV) yilentvirus edluliselwa ngeentlobano zesini enokukhokelela ekufumaneni iimmunodeficiency syndrome (uGawulayo), imeko ekhokelela ekusilelekeni ngokuthe ngcembe kwenkqubo yomzimba yokuzikhusela.Ukususela kwizalathisi zeklinikhi, iiseli ze-CD4 + T ezisegazini lomntu ezingaphezu kwama-200 zinentsholongwane kaGawulayo, kwaye ngaphantsi kwama-200 zigwetywa ngokuthe ngqo njengezigulana ze-AIDS.
Zimbini iindidi eziphambili ze-HIV, uhlobo loku-1 (HIV-I) kunye nohlobo lwesi-2 (HIV-II).Iintsholongwane ze-HIV-I zahlulwa kwakhona zibe ziintsholongwane ze-M, N, O, kunye ne-P. M zezona ziqhelekileyo kwaye zingoyena nobangela wobhubhane we-AIDS.Iintsholongwane zeKlasi O, "O" imele "ezingaphandle".
I-HIV ineendlela ezintathu zokosulela, ukosulela ngesondo, ukosulela ngegazi kunye nokosulela komntwana kumama.Phakathi kweendlela zosulelo lwesondo, ukosuleleka kwe-HIV ngokwabelana ngesondo kwabantu besini esinye kunokwenzeka ngakumbi.
Akukho sitofu sokugonya sikaGawulayo esisebenzayo.Nangona amayeza athomalalisa iintsholongwane esele ekho enokuyicinezela intsholongwane aze alibazise ngokunempumelelo ukwanda kwesifo, akakabikho amayeza anokunyanga ngokupheleleyo uGawulayo.
Uxilongo
Uxilongo lwaselabhoratri yeyona ndlela yokuqinisekisa usulelo lwe-HIV, kwaye iziphawuli ezithile ze-serological zinokubonwa kwangoko ngexesha losulelo:
I-HIV RNA: ifunyenwe ngeendlela ze-molekyuli, iintsuku ezili-11 emva kosulelo lwe-HIV
I-antigen ye-HIV-I-P24: ibonakala kwiintsuku ze-16 emva kosulelo
I-antibody ye-HIV: ifunyenwe kwiintsuku ezingama-22 zosulelo.
Kwinqanaba lokuqala losulelo (i-acute retrovirus syndrome), iimpawu ezinjengomkhuhlane zihamba kunye nokuphindaphinda ngokukhawuleza kwentsholongwane, enokuthi ibonwe egazini.Ukufunyanwa kwe-antigen ye-P24 (i-viral capsid protein) ihambelana ngokuthe ngqo nenani leentsholongwane ezijikelezayo (umthamo wentsholongwane) kubantu abosulelekileyo.
Ii-antibodies ezichasene neeprotheyini ezithile ze-HIV kunye ne-glycoproteins (umzekelo, i-p24, gp41, gp120) ziveliswa kwiiveki ezi-2-8 emva kosulelo kwaye ziyabonwa egazini emva koko.
Uvavanyo lokuhlola olusetyenziswa kakhulu ukubona ukuba sesichengeni se-HIV “luvavanyo lwe-HIV antibody”.Uvavanyo lokuqala lwamkelwa yi-FDA ngo-1985 kwaye luhlala luyenye yeendlela ezicetyiswayo ze-WHO zokuxilongwa kwe-HIV.Inkqubela phambili yetekhnoloji kunye nee-reagents ezibalulekileyo zenze ukuba kuphuhliswe isizukulwana esilandelayo sovavanyo lwe-HIV ukwenzela ukuba kubonwe kwangethuba nangokuchanekileyo ngakumbi abantu abosulelekileyo.Isizukulwana sesine sovavanyo lwe-HIV luyakwazi ukubona usulelo lwe-HIV kwiiveki ezi-3 ukuya kwezi-4 emva kokosulela ngokubhaqa omabini amajoni omzimba e-HIV kunye ne-p24.
Yintoni enokubonelela nge-Bio-Mapper?
Iqela leteknoloji ye-Maiyue Bio-Mapper lizinikele kwi-antigen ye-HIV kunye nophando lwe-antibody kunye nophuhliso iminyaka emininzi kwaye ithengise ngempumelelo uluhlu lweemveliso.Ukongeza ekuboneleleni ngezinto eziluhlaza ngegazi njengesampuli yovavanyo kwaye iyasebenza kwi-Immunochromatography / Flurescence Chromatography iqonga, i-Bio-Mapper inamandla okubonelela nge-antigen / antibody izinto ezisetyenziswa kwi-ELISA / Plate Luminescence platform, nakwi-platform ye-Tubular Magnetic Particle Chemiluminescence.Umgca wemveliso kaMaiyue Bio-Mapper utyebe kakhulu.
Eyeyona HIV (eKhawulezayo) uMthumeli ngaphandle kunye noMenzi |I-Bio-mapper (mapperbio.com
Eyona HIV (CMIA) Umthumeli ngaphandle kunye noMenzi |I-Bio-mapper (mapperbio.com)
Eyona HIV (CMIA) Umthumeli ngaphandle kunye noMenzi |I-Bio-mapper (mapperbio.com)
Eyona HIV (Abanye) Umthengisi ngaphandle kunye noMenzi |I-Bio-mapper (mapperbio.com)
Iindlela ezintathu zosulelo lwe-HIV zikhankanywe apha ngasentla, kwaye i-HIV, i-antigen ye-HIV, ibonwa ngezixa ezikhulu kumadlozi, kwincindi yelungu lobufazi, ulwelo lwe-preseminal, ulwelo lwe-rectal, igazi kunye nobisi lwebele.Nangona kunjalo, intsholongwane kagawulayo ayikho kumchamo wabantu abosulelwe yi-HIV, kwaye amanani alandelekayo kakhulu entsholongwane kaGawulayo anokubakho ematheni, umlinganiselo ogqithisileyo ukuze ubangwe usulelo.
Nangona ii-antigens ze-HIV zingekho okanye zikho ngemilinganiselo emincinane kakhulu kumchamo nakumathe, izixa ezithile zezilwa-buhlungu ze-HIV zinokubonwa kumchamo nakwizinkcwe zabantu abane-HIV.
I-antigen eyi-recombinant enikezelwe yi-Maiyue Bio-Mapper inokusetyenziselwa ukubona izilwa-buhlungu ze-HIV kumchamo kunye namathe.Phakathi kwezi, indawo ye-gp41 iyaqaphela izilwa-buhlungu ezibophelelayo ze-HIV-1 kwaye i-gp36 isetyenziselwa ukuqaphela izilwa-buhlungu ezinoveli ezibophelela i-HIV-2.Uvavanyo olwenziwa ixesha elide lokuvavanywa komchamo we-HIV kunye neemveliso zovavanyo lwamathe zinceda amaziko okhathalelo lwempilo ukuba enze uvavanyo lwangaphambili lwe-HIV ngokukhawuleza nangempumelelo.Kuba umntu oza kuvavanywa unokuqokelela amathe kunye neesampulu zomchamo eyedwa, imveliso inokufakwa kuvavanyo lokuzivavanya ekhaya, iphucula kakhulu indlela elula.Kwangaxeshanye, ngenxa yokuba uvavanyo aluna-invasive kwaye alunagazi (inani le-HIV egazini likhulu kwaye umngcipheko wokudlulisela i-AIIDS uphezulu kakhulu), akuyi kubakho ngxaki "yosulelo", kunye nomngcipheko wosulelo. Umvavanyi okanye abasebenzi bezonyango, umngcipheko wokuvezwa kwabasebenzi besampulu emsebenzini, kunye nomngcipheko wosulelo lwenkunkuma yezamayeza nako kunokuphetshwa.
Isiphelo:
Anti-ubhubhane, anti-AIDS ngaphezu.Iimveliso ze-HIV zovavanyo lwe-HIV ka-Maiyue Bio-Mapper ziya kuba negalelo kumandla amancinci kunobangela wolawulo lwe-AIDS kwihlabathi jikelele!
Isalathiso:Ingxelo yeNkqubela ye-AIDS ye-2022 yeGlobal: Amalungu abalulekileyo
Ixesha lokuposa: Dec-12-2022